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Compared with conventional therapy, endoscopic retrograde appendicitis therapy accelerates recovery, minimizes complications, and decreases hospital stay and overall healthcare expenditure in pediatric acute appendicitis.
A large-scale systematic review and meta-analysis has identified endoscopic retrograde appendicitis therapy (ERAT) as a highly effective, minimally invasive alternative for the treatment of acute appendicitis in children, illustrating faster recovery, fewer complications, shorter hospital stay, and lower healthcare costs when compared with conventional management. Shen Li and other researchers conducted a comprehensive search across 7 international electronic databases to determine the clinical efficacy of ERAT in pediatric acute appendicitis.
A total of 10 studies involving 1,372 pediatric patients were included:
The analysis revealed remarkable improvements across multiple perioperative and recovery outcomes like shorter operative time, higher fecalith detection rate, earlier postoperative feeding, lower postoperative white blood cell (WBC) count, faster normalization of WBC levels, quicker fever resolution, shorter duration of abdominal pain, decreased bed rest time, fewer postoperative complications, higher initial treatment success rate, shorter hospital stay, and minimized hospitalization costs. However, recurrence rates did not differ considerably between groups (Table 1).
The findings suggest that ERAT yields multiple advantages in tackling acute appendicitis in children, including:
As a minimally invasive, organ-preserving approach, ERAT may represent an evolving alternative to appendectomy in selected pediatric patients.
World Journal of Emergency Surgery
Clinical efficacy and safety of endoscopic retrograde appendicitis treatment for acute appendicitis in children: a systematic review and meta-analysis
Shen Li et al.
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