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Low-level laser therapy at 660 nm, 810 nm, and 975 nm wavelengths markedly alleviates pain in burning mouth syndrome patients, with the 810 nm and 975 nm wavelengths also notably improving numbness.
According to the outcomes of a study led by Xiao-Li Ge et al., low-level laser therapy (LLLT) at multiple wavelengths can successfully mitigate pain and numbness in burning mouth syndrome (BMS). The study found that all tested wavelengths led to significant pain relief, while specific wavelengths also improved numbness symptoms.
This single-blind randomized controlled trial assessed the usefulness of LLLT at three different wavelengths to determine the best approach for tackling BMS symptoms. Investigators enrolled 63 patients diagnosed with BMS, with 53 completing the treatment protocol. Volunteers were randomly assigned to one of three LLLT groups receiving treatment at wavelengths of 660 nm, 810 nm, or 975 nm.
Each patient underwent four weekly sessions of laser therapy, with parameters adjusted by wavelength: the 660 nm group (n=10) received 50 mW power at 1.5 J/cm² for 30 seconds per point; the 810 nm group (n=26) had 500 mW at 3 J/cm² for 6 seconds per point; and the 975 nm group (n=17) was treated with 30 mW at 10 J/cm² for 33 seconds per point. Researchers measured outcomes using a visual analog scale (VAS) to examine pain intensity, numbness, and altered taste sensations before and after treatment. Statistical analysis showed that all groups experienced substantial pain reduction, with a median decrease of 40%.
Notably, the 810 nm and 975 nm groups also reported a prominent 40% improvement in numbness symptoms. However, comparisons among the three wavelengths revealed no considerable differences in overall efficacy. Thus, LLLT is an effective option for ameliorating pain in BMS patients, with longer wavelengths potentially yielding additional relief for numbness. While the findings are encouraging, the trial highlights the requisition for further research to clarify if one wavelength offers superior benefits.
Lasers in Medical Science
Comparative efficacy of low-level diode laser therapy with different wavelengths in burning mouth syndrome: a randomized, single-blind trial
Xiao-Li Ge et al.
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