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A high-protein hypocaloric diet better preserves muscle mass and reduces body fat percentage than a conventional calorie-restricted diet in women with PCOS during short-term weight loss.
Women with polycystic ovary syndrome (PCOS) who followed a high-protein hypocaloric diet (HPD) during a 3-month weight loss program preserved considerably more muscle mass than those on a conventional calorie-restricted diet (CRD), according to a recent study conducted by Fang Wang et al.
The retrospective study analyzed data from 72 PCOS-affected woman who were overweight or obese and voluntarily initiated dietary interventions. Volunteers received either HPD or an isocaloric CRD with standard protein intake, and body composition and metabolic markers were assessed prior to and after the program.
While both groups experienced comparable weight loss, the HPD group retained more fat-free mass (FFM) and fat-free mass index (FFMI). Loss of FFM was considerably lower in the HPD group when compared to the CRD group. Similarly, FFMI decline was smaller in the HPD group. In addition, the HPD group attained a more substantial reduction in body fat percentage than the CRD group (Table 1).
Both dietary strategies resulted in improvements in metabolic markers such as serum lipids, glucose, insulin, and total testosterone, with no prominent differences observed between the two groups. The findings suggest that although both hypocaloric diets are beneficial for weight loss, a high-protein approach may offer added benefits in preserving muscle mass and optimizing body composition in women with PCOS. Researchers advocate for further well-designed trials to substantiate these results and explore long-term outcomes.
Diabetes, Metabolic Syndrome and Obesity
Evaluation of Effects of a High-Protein Hypocaloric Diet on Body Composition and Cardio-Metabolic Factors in Women with Polycystic Ovary Syndrome and Overweight or Obesity
Fang Wang et al.
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